| Viernes 1 de enero de 2021: | |||||
| Everton | – | West Ham United | 0 | – | 1 |
| Manchester United | – | Aston Villa | 2 | – | 1 |
| Sábado 2 de enero de 2021: | |||||
| Tottenham Hotspur | – | 3 | – | 0 | |
| Crystal Palace | – | Sheffield United | 2 | – | 0 |
| Brighton & Hove Albion | – | Wolverhampton | 3 | – | 3 |
| West Bromwich Albion | – | Arsenal | 0 | – | 4 |
| Domingo 3 de enero de 2021: | |||||
| Burnley | – | Fulham | Cancelado | ||
| Newcastle United | – | Leicester City | 1 | – | 2 |
| Chelsea | – | Manchester City | 1 | – | 3 |
| Lunes 4 de enero de 2021: | |||||
| Southampton | – | Liverpool | 20:00 | ||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Liverpool | 16 | 9 | 6 | 1 | 37-20 | 33 |
| 2. | Manchester United | 16 | 10 | 3 | 3 | 33-24 | 33 |
| 3. | Leicester City | 17 | 10 | 2 | 5 | 31-21 | 32 |
| 4. | Tottenham Hotspur | 16 | 8 | 5 | 3 | 29-15 | 29 |
| 5. | Manchester City | 15 | 8 | 5 | 2 | 24-13 | 29 |
| 6. | Everton | 16 | 9 | 2 | 5 | 26-20 | 29 |
| 7. | Aston Villa | 15 | 8 | 2 | 5 | 29-16 | 26 |
| 8. | Chelsea | 17 | 7 | 5 | 5 | 32-21 | 26 |
| 9. | Southampton | 16 | 7 | 5 | 4 | 25-19 | 26 |
| 10. | West Ham United | 17 | 7 | 5 | 5 | 24-21 | 26 |
| 11. | Arsenal | 17 | 7 | 2 | 8 | 20-19 | 23 |
| 12. | 17 | 7 | 2 | 8 | 30-33 | 23 | |
| 13. | Wolverhampton | 17 | 6 | 4 | 7 | 18-24 | 22 |
| 14. | Crystal Palace | 17 | 6 | 4 | 7 | 22-29 | 22 |
| 15. | Newcastle United | 16 | 5 | 4 | 7 | 18-26 | 19 |
| 16. | Burnley | 15 | 4 | 4 | 7 | 9-20 | 16 |
| 17. | Brighton & Hove Albion | 17 | 2 | 8 | 7 | 21-28 | 14 |
| 18. | Fulham | 15 | 2 | 5 | 8 | 13-23 | 11 |
| 19. | West Bromwich Albion | 17 | 1 | 5 | 11 | 11-39 | 8 |
| 20. | Sheffield United | 17 | 0 | 2 | 15 | 8-29 | 2 |
