| Sábado 9 de enero de 2021: | |||||
| Benevento Calcio | – | Atalanta | 1 | – | 4 |
| Genoa | – | Bologna | 2 | – | 0 |
| Milan | – | Torino | 2 | – | 0 |
| Domingo 10 de enero de 2021: | |||||
| Roma | – | Inter de Milán | 2 | – | 2 |
| Parma | – | Lazio | 0 | – | 2 |
| Udinese | – | Napoli | 1 | – | 2 |
| Hellas Verona | – | Crotone | 2 | – | 1 |
| Fiorentina | – | Cagliari | 1 | – | 0 |
| Juventus | – | Sassuolo | 19:45 | ||
| Lunes 11 de enero de 2021: | |||||
| – | Sampdoria | 19:45 | |||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Milan | 17 | 12 | 4 | 1 | 37-19 | 40 |
| 2. | Inter de Milán | 17 | 11 | 4 | 2 | 43-23 | 37 |
| 3. | Roma | 17 | 10 | 4 | 3 | 37-26 | 34 |
| 4. | Atalanta | 16 | 9 | 4 | 3 | 40-22 | 31 |
| 5. | Napoli | 16 | 10 | 1 | 5 | 34-16 | 31 |
| 6. | Juventus | 15 | 8 | 6 | 1 | 32-15 | 30 |
| 7. | Sassuolo | 16 | 8 | 5 | 3 | 29-23 | 29 |
| 8. | Lazio | 17 | 8 | 4 | 5 | 27-25 | 28 |
| 9. | Hellas Verona | 17 | 7 | 6 | 4 | 22-16 | 27 |
| 10. | Benevento Calcio | 17 | 6 | 3 | 8 | 20-30 | 21 |
| 11. | Sampdoria | 16 | 6 | 2 | 8 | 25-26 | 20 |
| 12. | Fiorentina | 17 | 4 | 6 | 7 | 18-23 | 18 |
| 13. | Bologna | 17 | 4 | 5 | 8 | 23-31 | 17 |
| 14. | Udinese | 16 | 4 | 4 | 8 | 18-25 | 16 |
| 15. | 16 | 3 | 5 | 8 | 21-31 | 14 | |
| 16. | Cagliari | 17 | 3 | 5 | 9 | 23-34 | 14 |
| 17. | Genoa | 17 | 3 | 5 | 9 | 18-30 | 14 |
| 18. | Torino | 17 | 2 | 6 | 9 | 26-35 | 12 |
| 19. | Parma | 17 | 2 | 6 | 9 | 13-33 | 12 |
| 20. | Crotone | 17 | 2 | 3 | 12 | 17-40 | 9 |
