| Viernes 5 de febrero de 2021: | |||||
| Hertha Berlin | – | Bayern Múnich | 0 | – | 1 |
| Sábado 6 de febrero de 2021: | |||||
| Bayer Leverkusen | – | Stuttgart | 5 | – | 2 |
| Freiburg | – | Borussia Dortmund | 2 | – | 1 |
| Schalke | – | Leipzig | 0 | – | 3 |
| Mainz | – | Union Berlin | 1 | – | 0 |
| Augsburgo | – | Wolfsburgo | 0 | – | 2 |
| Bor. Mönchengladbach | – | Colonia | 1 | – | 2 |
| Domingo 7 de febrero de 2021: | |||||
| Hoffenheim | – | Eintracht Fráncfort | 14:30 | ||
| Arminia Bielefeld | – | Werder Bremen | Cancelado | ||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Bayern Múnich | 20 | 15 | 3 | 2 | 58-26 | 48 |
| 2. | Leipzig | 20 | 12 | 5 | 3 | 35-17 | 41 |
| 3. | Wolfsburgo | 20 | 10 | 8 | 2 | 32-19 | 38 |
| 4. | Bayer Leverkusen | 20 | 10 | 5 | 5 | 37-21 | 35 |
| 5. | Eintracht Fráncfort | 19 | 8 | 9 | 2 | 38-28 | 33 |
| 6. | Borussia Dortmund | 20 | 10 | 2 | 8 | 39-29 | 32 |
| 7. | Bor. Mönchengladbach | 20 | 8 | 8 | 4 | 37-31 | 32 |
| 8. | Freiburg | 20 | 8 | 6 | 6 | 35-33 | 30 |
| 9. | Union Berlin | 20 | 7 | 8 | 5 | 34-25 | 29 |
| 10. | Stuttgart | 20 | 6 | 7 | 7 | 37-34 | 25 |
| 11. | Werder Bremen | 19 | 5 | 7 | 7 | 24-27 | 22 |
| 12. | Hoffenheim | 19 | 6 | 4 | 9 | 29-34 | 22 |
| 13. | Augsburgo | 20 | 6 | 4 | 10 | 20-32 | 22 |
| 14. | Colonia | 20 | 5 | 6 | 9 | 20-33 | 21 |
| 15. | Hertha Berlin | 20 | 4 | 5 | 11 | 25-36 | 17 |
| 16. | Arminia Bielefeld | 19 | 5 | 2 | 12 | 15-32 | 17 |
| 17. | Mainz | 20 | 3 | 4 | 13 | 19-40 | 13 |
| 18. | Schalke | 20 | 1 | 5 | 14 | 15-52 | 8 |
