| Viernes 19 de febrero de 2021: | |||||
| Wolverhampton | – | 1 | – | 0 | |
| Sábado 20 de febrero de 2021: | |||||
| Southampton | – | Chelsea | 1 | – | 1 |
| Burnley | – | West Bromwich Albion | 0 | – | 0 |
| Liverpool | – | Everton | 0 | – | 2 |
| Fulham | – | Sheffield United | 1 | – | 0 |
| Domingo 21 de febrero de 2021: | |||||
| West Ham United | – | Tottenham Hotspur | 2 | – | 1 |
| Aston Villa | – | Leicester City | 1 | – | 2 |
| Arsenal | – | Manchester City | 0 | – | 1 |
| Manchester United | – | Newcastle United | 3 | – | 1 |
| Lunes 22 de febrero de 2021: | |||||
| Brighton & Hove Albion | – | Crystal Palace | 20:00 | ||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Manchester City | 25 | 18 | 5 | 2 | 50-15 | 59 |
| 2. | Manchester United | 25 | 14 | 7 | 4 | 53-32 | 49 |
| 3. | Leicester City | 25 | 15 | 4 | 6 | 44-27 | 49 |
| 4. | West Ham United | 25 | 13 | 6 | 6 | 39-29 | 45 |
| 5. | Chelsea | 25 | 12 | 7 | 6 | 41-25 | 43 |
| 6. | Liverpool | 25 | 11 | 7 | 7 | 45-34 | 40 |
| 7. | Everton | 24 | 12 | 4 | 8 | 37-33 | 40 |
| 8. | Aston Villa | 23 | 11 | 3 | 9 | 37-26 | 36 |
| 9. | Tottenham Hotspur | 24 | 10 | 6 | 8 | 37-27 | 36 |
| 10. | Arsenal | 25 | 10 | 4 | 11 | 31-26 | 34 |
| 11. | Wolverhampton | 25 | 9 | 6 | 10 | 26-32 | 33 |
| 12. | 24 | 10 | 2 | 12 | 40-43 | 32 | |
| 13. | Southampton | 24 | 8 | 6 | 10 | 31-40 | 30 |
| 14. | Crystal Palace | 24 | 8 | 5 | 11 | 27-42 | 29 |
| 15. | Burnley | 25 | 7 | 7 | 11 | 18-30 | 28 |
| 16. | Brighton & Hove Albion | 24 | 5 | 11 | 8 | 25-30 | 26 |
| 17. | Newcastle United | 25 | 7 | 4 | 14 | 26-43 | 25 |
| 18. | Fulham | 25 | 4 | 10 | 11 | 21-32 | 22 |
| 19. | West Bromwich Albion | 25 | 2 | 8 | 15 | 19-55 | 14 |
| 20. | Sheffield United | 25 | 3 | 2 | 20 | 15-41 | 11 |
