| Viernes 26 de febrero de 2021: | |||||
| Werder Bremen | – | Eintracht Fráncfort | 2 | – | 1 |
| Sábado 27 de febrero de 2021: | |||||
| Bayern Múnich | – | Colonia | 5 | – | 1 |
| Borussia Dortmund | – | Arminia Bielefeld | 3 | – | 0 |
| Wolfsburgo | – | Hertha Berlin | 2 | – | 0 |
| Stuttgart | – | Schalke | 5 | – | 1 |
| Leipzig | – | Bor. Mönchengladbach | 3 | – | 2 |
| Domingo 28 de febrero de 2021: | |||||
| Union Berlin | – | Hoffenheim | 1 | – | 1 |
| Mainz | – | Augsburgo | 0 | – | 1 |
| Bayer Leverkusen | – | Freiburg | 1 | – | 2 |
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Bayern Múnich | 23 | 16 | 4 | 3 | 67-32 | 52 |
| 2. | Leipzig | 23 | 15 | 5 | 3 | 43-20 | 50 |
| 3. | Wolfsburgo | 23 | 12 | 9 | 2 | 37-19 | 45 |
| 4. | Eintracht Fráncfort | 23 | 11 | 9 | 3 | 46-32 | 42 |
| 5. | Borussia Dortmund | 23 | 12 | 3 | 8 | 48-31 | 39 |
| 6. | Bayer Leverkusen | 23 | 10 | 7 | 6 | 41-26 | 37 |
| 7. | Union Berlin | 23 | 8 | 10 | 5 | 36-26 | 34 |
| 8. | Freiburg | 23 | 9 | 7 | 7 | 37-35 | 34 |
| 9. | Bor. Mönchengladbach | 23 | 8 | 9 | 6 | 40-36 | 33 |
| 10. | Stuttgart | 23 | 8 | 8 | 7 | 44-36 | 32 |
| 11. | Hoffenheim | 23 | 7 | 6 | 10 | 37-40 | 27 |
| 12. | Werder Bremen | 22 | 6 | 8 | 8 | 26-32 | 26 |
| 13. | Augsburgo | 23 | 7 | 5 | 11 | 23-35 | 26 |
| 14. | Colonia | 23 | 5 | 6 | 12 | 21-41 | 21 |
| 15. | Hertha Berlin | 23 | 4 | 6 | 13 | 26-42 | 18 |
| 16. | Arminia Bielefeld | 22 | 5 | 3 | 14 | 18-41 | 18 |
| 17. | Mainz | 23 | 4 | 5 | 14 | 23-44 | 17 |
| 18. | Schalke | 23 | 1 | 6 | 16 | 16-61 | 9 |
