| Sábado 10 de abril de 2021: | |||||
| Spezia | – | Crotone | 3 | – | 2 |
| Parma | – | Milan | 1 | – | 3 |
| Udinese | – | Torino | 0 | – | 1 |
| Domingo 11 de abril de 2021: | |||||
| Inter de Milán | – | Cagliari | 1 | – | 0 |
| Juventus | – | Genoa | 3 | – | 1 |
| Hellas Verona | – | Lazio | 0 | – | 1 |
| Sampdoria | – | Napoli | 0 | – | 2 |
| Roma | – | Bologna | 1 | – | 0 |
| Fiorentina | – | Atalanta | 2 | – | 3 |
| Lunes 12 de abril de 2021: | |||||
| Benevento Calcio | – | Sassuolo | 18:45 | ||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Inter de Milán | 30 | 23 | 5 | 2 | 69-27 | 74 |
| 2. | Milan | 30 | 19 | 6 | 5 | 57-35 | 63 |
| 3. | Juventus | 30 | 18 | 8 | 4 | 61-27 | 62 |
| 4. | Atalanta | 30 | 18 | 7 | 5 | 71-38 | 61 |
| 5. | Napoli | 30 | 19 | 2 | 9 | 65-34 | 59 |
| 6. | Lazio | 29 | 17 | 4 | 8 | 46-38 | 55 |
| 7. | Roma | 30 | 16 | 6 | 8 | 54-44 | 54 |
| 8. | Hellas Verona | 30 | 11 | 8 | 11 | 38-35 | 41 |
| 9. | Sassuolo | 29 | 10 | 10 | 9 | 48-48 | 40 |
| 10. | Sampdoria | 30 | 10 | 6 | 14 | 39-45 | 36 |
| 11. | Bologna | 30 | 9 | 7 | 14 | 39-46 | 34 |
| 12. | Udinese | 30 | 8 | 9 | 13 | 32-40 | 33 |
| 13. | Genoa | 30 | 7 | 11 | 12 | 32-44 | 32 |
| 14. | Spezia | 30 | 8 | 8 | 14 | 40-55 | 32 |
| 15. | Fiorentina | 30 | 7 | 9 | 14 | 38-49 | 30 |
| 16. | Benevento Calcio | 29 | 7 | 9 | 13 | 30-54 | 30 |
| 17. | Torino | 29 | 5 | 12 | 12 | 42-52 | 27 |
| 18. | Cagliari | 30 | 5 | 7 | 18 | 31-51 | 22 |
| 19. | Parma | 30 | 3 | 11 | 16 | 29-59 | 20 |
| 20. | Crotone | 30 | 4 | 3 | 23 | 37-77 | 15 |
