| Viernes 19 de noviembre de 2021: | |||||
| Augsburgo | – | Bayern Múnich | 2 | – | 1 |
| Sábado 20 de noviembre de 2021: | |||||
| Borussia Dortmund | – | Stuttgart | 2 | – | 1 |
| Bayer Leverkusen | – | Bochum | 1 | – | 0 |
| Bor. Mönchengladbach | – | Greuther Fürth | 4 | – | 0 |
| Hoffenheim | – | Leipzig | 2 | – | 0 |
| Arminia Bielefeld | – | Wolfsburgo | 2 | – | 2 |
| Union Berlin | – | Hertha Berlin | 2 | – | 0 |
| Domingo 21 de noviembre de 2021: | |||||
| Freiburg | – | Eintracht Fráncfort | 0 | – | 2 |
| Mainz | – | Colonia | 1 | – | 1 |
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Bayern Múnich | 12 | 9 | 1 | 2 | 41-13 | 28 |
| 2. | Borussia Dortmund | 12 | 9 | 0 | 3 | 30-18 | 27 |
| 3. | Freiburg | 12 | 6 | 4 | 2 | 18-11 | 22 |
| 4. | Bayer Leverkusen | 12 | 6 | 3 | 3 | 25-17 | 21 |
| 5. | Union Berlin | 12 | 5 | 5 | 2 | 19-17 | 20 |
| 6. | Wolfsburgo | 12 | 6 | 2 | 4 | 14-14 | 20 |
| 7. | Leipzig | 12 | 5 | 3 | 4 | 23-13 | 18 |
| 8. | Mainz | 12 | 5 | 3 | 4 | 16-12 | 18 |
| 9. | Bor. Mönchengladbach | 12 | 5 | 3 | 4 | 17-14 | 18 |
| 10. | Hoffenheim | 12 | 5 | 2 | 5 | 21-17 | 17 |
| 11. | Eintracht Fráncfort | 12 | 3 | 6 | 3 | 14-16 | 15 |
| 12. | Colonia | 12 | 3 | 6 | 3 | 18-21 | 15 |
| 13. | Bochum | 12 | 4 | 1 | 7 | 10-19 | 13 |
| 14. | Hertha Berlin | 12 | 4 | 1 | 7 | 12-26 | 13 |
| 15. | Augsburgo | 12 | 3 | 3 | 6 | 11-21 | 12 |
| 16. | Stuttgart | 12 | 2 | 4 | 6 | 16-22 | 10 |
| 17. | Arminia Bielefeld | 12 | 1 | 6 | 5 | 9-18 | 9 |
| 18. | Greuther Fürth | 12 | 0 | 1 | 11 | 8-33 | 1 |
