| Viernes 19 de noviembre de 2021: | |||||
| Mónaco | – | Lille | 2 | – | 2 |
| Sábado 20 de noviembre de 2021: | |||||
| Paris Saint Germain | – | Nantes | 3 | – | 1 |
| Stade Rennes | – | Montpellier | 2 | – | 0 |
| Domingo 21 de noviembre de 2021: | |||||
| Stade Brest | – | Lens | 4 | – | 0 |
| Troyes | – | Saint Etienne | 0 | – | 1 |
| Metz | – | Girondins de Burdeos | 3 | – | 3 |
| Racing Estrasburgo | – | Stade de Reims | 1 | – | 1 |
| Angers | – | Lorient | 1 | – | 0 |
| – | Niza | 1 | – | 2 | |
| Olympique de Lyon | – | Olympique de Marsellla | 19:45 | ||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Paris Saint Germain | 14 | 12 | 1 | 1 | 32-14 | 37 |
| 2. | Niza | 14 | 8 | 3 | 3 | 25-11 | 26 |
| 3. | Stade Rennes | 14 | 7 | 4 | 3 | 24-12 | 25 |
| 4. | Lens | 14 | 7 | 3 | 4 | 25-18 | 24 |
| 5. | Olympique de Marsellla | 13 | 6 | 5 | 2 | 20-12 | 23 |
| 6. | Angers | 14 | 5 | 6 | 3 | 20-16 | 21 |
| 7. | Racing Estrasburgo | 14 | 5 | 4 | 5 | 25-19 | 19 |
| 8. | Mónaco | 14 | 5 | 4 | 5 | 19-18 | 19 |
| 9. | Montpellier | 14 | 5 | 4 | 5 | 21-21 | 19 |
| 9. | Olympique de Lyon | 13 | 5 | 4 | 4 | 21-21 | 19 |
| 11. | Nantes | 14 | 5 | 3 | 6 | 19-19 | 18 |
| 12. | Lille | 14 | 4 | 5 | 5 | 18-21 | 17 |
| 13. | Stade Brest | 14 | 3 | 6 | 5 | 20-21 | 15 |
| 14. | Lorient | 14 | 3 | 6 | 5 | 13-21 | 15 |
| 15. | Stade de Reims | 14 | 2 | 7 | 5 | 15-18 | 13 |
| 16. | Girondins de Burdeos | 14 | 2 | 7 | 5 | 21-30 | 13 |
| 17. | Troyes | 14 | 3 | 4 | 7 | 13-22 | 13 |
| 18. | 14 | 3 | 4 | 7 | 17-28 | 13 | |
| 19. | Saint Etienne | 14 | 2 | 6 | 6 | 16-28 | 12 |
| 20. | Metz | 14 | 1 | 6 | 7 | 16-30 | 9 |
