| Viernes 26 de noviembre de 2021: | |||||
| Stuttgart | – | Mainz | 2 | – | 1 |
| Sábado 27 de noviembre de 2021: | |||||
| Wolfsburgo | – | Borussia Dortmund | 1 | – | 3 |
| Hertha Berlin | – | Augsburgo | 1 | – | 1 |
| Colonia | – | Bor. Mönchengladbach | 4 | – | 1 |
| Bochum | – | Freiburg | 2 | – | 1 |
| Greuther Fürth | – | Hoffenheim | 3 | – | 6 |
| Bayern Múnich | – | Arminia Bielefeld | 1 | – | 0 |
| Domingo 28 de noviembre de 2021: | |||||
| Eintracht Fráncfort | – | Union Berlin | 2 | – | 1 |
| Leipzig | – | Bayer Leverkusen | 1 | – | 3 |
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Bayern Múnich | 13 | 10 | 1 | 2 | 42-13 | 31 |
| 2. | Borussia Dortmund | 13 | 10 | 0 | 3 | 33-19 | 30 |
| 3. | Bayer Leverkusen | 13 | 7 | 3 | 3 | 28-18 | 24 |
| 4. | Freiburg | 13 | 6 | 4 | 3 | 19-13 | 22 |
| 5. | Hoffenheim | 13 | 6 | 2 | 5 | 27-20 | 20 |
| 6. | Union Berlin | 13 | 5 | 5 | 3 | 20-19 | 20 |
| 7. | Wolfsburgo | 13 | 6 | 2 | 5 | 15-17 | 20 |
| 8. | Leipzig | 13 | 5 | 3 | 5 | 24-16 | 18 |
| 9. | Mainz | 13 | 5 | 3 | 5 | 17-14 | 18 |
| 10. | Colonia | 13 | 4 | 6 | 3 | 22-22 | 18 |
| 11. | Bor. Mönchengladbach | 13 | 5 | 3 | 5 | 18-18 | 18 |
| 12. | Eintracht Fráncfort | 13 | 4 | 6 | 3 | 16-17 | 18 |
| 13. | Bochum | 13 | 5 | 1 | 7 | 12-20 | 16 |
| 14. | Hertha Berlin | 13 | 4 | 2 | 7 | 13-27 | 14 |
| 15. | Stuttgart | 13 | 3 | 4 | 6 | 18-23 | 13 |
| 16. | Augsburgo | 13 | 3 | 4 | 6 | 12-22 | 13 |
| 17. | Arminia Bielefeld | 13 | 1 | 6 | 6 | 9-19 | 9 |
| 18. | Greuther Fürth | 13 | 0 | 1 | 12 | 11-39 | 1 |
