| Viernes 14 de enero de 2022: | |||||
| Borussia Dortmund | – | Freiburg | 5 | – | 1 |
| Sábado 15 de enero de 2022: | |||||
| Wolfsburgo | – | Hertha Berlin | 0 | – | 0 |
| Union Berlin | – | Hoffenheim | 2 | – | 1 |
| Stuttgart | – | Leipzig | 0 | – | 2 |
| Mainz | – | Bochum | 1 | – | 0 |
| Colonia | – | Bayern Múnich | 0 | – | 4 |
| Bor. Mönchengladbach | – | Bayer Leverkusen | 1 | – | 2 |
| Domingo 16 de enero de 2022: | |||||
| Augsburgo | – | Eintracht Fráncfort | 1 | – | 1 |
| Arminia Bielefeld | – | Greuther Fürth | 2 | – | 2 |
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Bayern Múnich | 19 | 15 | 1 | 3 | 61-18 | 46 |
| 2. | Borussia Dortmund | 19 | 13 | 1 | 5 | 49-29 | 40 |
| 3. | Bayer Leverkusen | 19 | 9 | 5 | 5 | 44-31 | 32 |
| 4. | Hoffenheim | 19 | 9 | 4 | 6 | 39-29 | 31 |
| 5. | Union Berlin | 19 | 8 | 7 | 4 | 27-24 | 31 |
| 6. | Freiburg | 19 | 8 | 6 | 5 | 31-23 | 30 |
| 7. | Leipzig | 19 | 8 | 4 | 7 | 36-23 | 28 |
| 8. | Eintracht Fráncfort | 19 | 7 | 7 | 5 | 30-28 | 28 |
| 9. | Colonia | 19 | 7 | 7 | 5 | 30-32 | 28 |
| 10. | Mainz | 19 | 8 | 3 | 8 | 27-21 | 27 |
| 11. | Bochum | 19 | 7 | 2 | 10 | 17-27 | 23 |
| 12. | Bor. Mönchengladbach | 19 | 6 | 4 | 9 | 25-35 | 22 |
| 13. | Hertha Berlin | 19 | 6 | 4 | 9 | 21-38 | 22 |
| 14. | Wolfsburgo | 19 | 6 | 3 | 10 | 17-30 | 21 |
| 15. | Augsburgo | 19 | 4 | 7 | 8 | 19-30 | 19 |
| 16. | Arminia Bielefeld | 19 | 3 | 9 | 7 | 18-26 | 18 |
| 17. | Stuttgart | 19 | 4 | 6 | 9 | 22-33 | 18 |
| 18. | Greuther Fürth | 19 | 1 | 4 | 14 | 15-51 | 7 |
