Resultados y tabla de posiciones de la Liga italiana de fútbol (hora de inicio de los partidos en GMT):
| Sábado 15 de enero de 2022: | |||||
| Sampdoria | – | Torino | 1 | – | 2 |
| – | Lazio | 0 | – | 3 | |
| Juventus | – | Udinese | 2 | – | 0 |
| Domingo 16 de enero de 2022: | |||||
| Sassuolo | – | Hellas Verona | 2 | – | 4 |
| – | Empoli | 1 | – | 1 | |
| Roma | – | Cagliari | 1 | – | 0 |
| Atalanta | – | Inter de Milán | 0 | – | 0 |
| Lunes 17 de enero de 2022: | |||||
| Milan | – | Spezia | 17:30 | ||
| Bologna | – | Napoli | 17:30 | ||
| Fiorentina | – | Genoa | 19:45 | ||
| EQUIPO | J | G | E | P | Goles | Pts | |
| 1. | Inter de Milán | 21 | 15 | 5 | 1 | 51-16 | 50 |
| 2. | Milan | 21 | 15 | 3 | 3 | 46-23 | 48 |
| 3. | Napoli | 21 | 13 | 4 | 4 | 37-15 | 43 |
| 4. | Atalanta | 21 | 12 | 6 | 3 | 44-26 | 42 |
| 5. | Juventus | 22 | 12 | 5 | 5 | 34-21 | 41 |
| 6. | Lazio | 22 | 10 | 5 | 7 | 46-39 | 35 |
| 7. | Roma | 22 | 11 | 2 | 9 | 36-28 | 35 |
| 8. | Fiorentina | 20 | 10 | 2 | 8 | 34-29 | 32 |
| 9. | Torino | 21 | 9 | 4 | 8 | 29-20 | 31 |
| 10. | Hellas Verona | 22 | 8 | 6 | 8 | 41-37 | 30 |
| 11. | Empoli | 22 | 8 | 5 | 9 | 35-43 | 29 |
| 12. | Sassuolo | 22 | 7 | 7 | 8 | 38-37 | 28 |
| 13. | Bologna | 20 | 8 | 3 | 9 | 28-33 | 27 |
| 14. | Udinese | 20 | 4 | 8 | 8 | 28-36 | 20 |
| 15. | Sampdoria | 22 | 5 | 5 | 12 | 29-40 | 20 |
| 16. | Spezia | 21 | 5 | 4 | 12 | 21-41 | 19 |
| 17. | 21 | 4 | 6 | 11 | 19-38 | 18 | |
| 18. | Cagliari | 22 | 3 | 7 | 12 | 21-43 | 16 |
| 19. | Genoa | 21 | 1 | 9 | 11 | 20-39 | 12 |
| 20. | 20 | 3 | 2 | 15 | 13-46 | 11 |
